SCHEMBL8975469

N=C(N)NCCC[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O

nearest known ligand 0.73

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	16/20	0.73

▸	NPY1R	P25929	10/20	0.73

▸	NPY5R	Q15761	9/20	0.73

▸	NPY2R	P49146	6/20	0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29483774	1.00	NPY4R (0.73)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL29641108	0.98	NPY4R (0.76)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL29641194	0.98	NPY4R (0.76)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL29641115	0.98	NPY4R (0.76)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL29641126	0.98	NPY4R (0.76)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL29641019	0.98	NPY4R (0.76)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL26179144	0.98	NPY4R (0.76)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL29641098	0.96	NPY4R (0.68)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL29641056	0.96	NPY4R (0.68)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL8975803	0.96	NPY4R (0.68)	NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0350221-B1	Dermorphin analogs, their methods of preparation, pharmaceutical compositions, and methods of therapeutic treatment using the same	ASTRA AB (SE)	1996-04-17	—	—	EP	disclosed
EP-0350221-A2	Dermorphin analogs, their methods of preparation, pharmaceutical compositions, and methods of therapeutic treatment using the same	Astra Aktiebolag (SE)	1990-01-10	—	—	EP	disclosed