Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24103788 | 1.00 | BRD4 (0.42) | BRD4BRD2MBOAT4NPC1POLB | |
| SCHEMBL30522525 | 0.74 | MAP4K4 (0.43) | BRD4BRD2MBOAT4NPC1POLB | |
| SCHEMBL15206943 | 0.72 | BRD4 (0.44) | BRD4BRD2MBOAT4CYP1A2CYP3A4 | |
| SCHEMBL18249941 | 0.71 | FFAR1 (0.43) | BRD4BRD2NPC1POLBCASP3 | |
| SCHEMBL16404611 | 0.69 | BRD4 (0.56) | BRD4BRD2NPC1POLBCASP3 | |
| SCHEMBL12362771 | 0.69 | BRD4 (0.49) | BRD4BRD2ARBTKCYP1A2 | |
| SCHEMBL19754246 | 0.68 | BRD4 (0.46) | BRD4BRD2MBOAT4NPC1POLB | |
| SCHEMBL29836739 | 0.68 | BRD4 (0.46) | BRD4BRD2MBOAT4ARJAK2 | |
| SCHEMBL27321340 | 0.67 | KDM4E (0.36) | NOS3NOS1NOS2 | |
| SCHEMBL13036090 | 0.67 | NPC1 (0.47) | BRD4BRD2NPC1POLBCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116209664-A | Small molecule modulators of IL-17 | 利奥制药有限公司 | 2023-06-02 | — | — | CN | disclosed |