Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 8/20 | 0.42 |
| ▸ | BRD2 | P25440 | 3/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18249941 | 0.87 | FFAR1 (0.43) | MAP4K4BRD4BRD2ARJAK2 | |
| SCHEMBL11980660 | 0.80 | BRD4 (0.47) | MAP4K4BRD4BRD2ARJAK2 | |
| SCHEMBL16896898 | 0.78 | BRD4 (0.48) | BRD4BRD2ERN1ATAD2BRD3 | |
| SCHEMBL18249919 | 0.77 | NR3C1 (0.43) | MAP4K4BRD4BRD2ARJAK2 | |
| SCHEMBL16118502 | 0.77 | ERN1 (0.48) | MAP4K4BRD4BRD2ARJAK2 | |
| SCHEMBL15445884 | 0.77 | BRD4 (0.45) | BRD4BRD2BTKERN1CYP1A2 | |
| SCHEMBL16404611 | 0.76 | BRD4 (0.56) | BRD4BRD2BRD3NPC1POLB | |
| SCHEMBL19552215 | 0.76 | BRD4 (0.57) | MAP4K4BRD4BRD2ARERN1 | |
| SCHEMBL1906132 | 0.75 | BRD4 (0.48) | BRD4BRD2ERN1ATAD2BRD3 | |
| SCHEMBL18249917 | 0.75 | BRD4 (0.43) | MAP4K4BRD4BRD2ARJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116547275-A | IL-17A modulators | 赛诺菲 | 2023-08-04 | — | — | CN | disclosed |