SCHEMBL30420873

CC(=O)N[C@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O

nearest known ligand 0.76

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	KISS1R	Q969F8	20/20	0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30420969	1.00	KISS1R (0.76)	KISS1R
SCHEMBL30420526	1.00	KISS1R (0.76)	KISS1R
SCHEMBL30421283	1.00	KISS1R (0.76)	KISS1R
SCHEMBL30420870	1.00	KISS1R (0.76)	KISS1R
SCHEMBL30421347	1.00	KISS1R (0.76)	KISS1R
SCHEMBL29657318	0.93	KISS1R (0.78)	KISS1R
SCHEMBL15930214	0.93	KISS1R (0.78)	KISS1R
SCHEMBL30530935	0.93	KISS1R (0.82)	KISS1R
SCHEMBL30845358	0.93	KISS1R (0.74)	KISS1R
SCHEMBL30420814	0.91	KISS1R (0.66)	KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4430064-A1	CYCLIC PEPTIDE COMPOUNDS WHICH ARE KISS1R RECEPTOR AGONISTS, AND THERAPEUTIC USES THEREOF	Institut national de recherche pour l'agriculture, l'alimentation et l'environnement (FR)	2024-09-18	—	—	EP	disclosed
WO-2023083815-A1	CYCLIC PEPTIDE COMPOUNDS WHICH ARE KISS1R RECEPTOR AGONISTS, AND THERAPEUTIC USES THEREOF	INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE L'ALIMENTATION ET L'ENVIRONNEMENT (FR)	2023-05-19	—	—	WO	disclosed