SCHEMBL30422766

CC[C@H](C)[C@H](NC(=O)[C@H](COC(C)(C)C)NC(=O)[C@H](Cc1ccc(OC(C)(C)C)cc1)NC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)[C@H](COC(C)(C)C)NC(=O)[C@@H](N)[C@@H](C)OC(C)(C)C)C(=O)NC(C)(C)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	CTSD	P07339	7/20	0.42

▸	ABCB1	P08183	1/20	0.39

▸	MMP1	P03956	1/20	0.36

▸	REN	P00797	9/20	0.35

▸	PTPN1	P18031	1/20	0.34

▸	PSEN1	P49768	2/20	0.33

▸	PSEN2	P49810	2/20	0.33

▸	APH1B	Q8WW43	2/20	0.33

▸	NCSTN	Q92542	2/20	0.33

▸	APH1A	Q96BI3	2/20	0.33

▸	PSENEN	Q9NZ42	2/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29468876	0.92	CTSD (0.41)	CTSDABCB1MMP1PTPN1
SCHEMBL30422838	0.92	CTSD (0.42)	CTSDABCB1MMP1RENPTPN1
SCHEMBL30422261	0.90	CTSD (0.43)	CTSDABCB1MMP1REN
SCHEMBL31518742	0.88	PSEN1 (0.42)	CTSDRENPSEN1PSEN2APH1B
SCHEMBL30647289	0.85	ABCB1 (0.43)	ABCB1MMP1REN
SCHEMBL29468879	0.83	ABCB1 (0.41)	CTSDABCB1MMP1PTPN1
SCHEMBL29468820	0.81	ABCB1 (0.42)	CTSDABCB1MMP1PTPN1
SCHEMBL30422538	0.80	CTSD (0.44)	CTSDABCB1MMP1REN
SCHEMBL30422599	0.80	CTSD (0.44)	CTSDABCB1MMP1REN
SCHEMBL30250381	0.78	CTSD (0.42)	CTSDREN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4146248-A1	LONG ACTING GLP-1/GIP DUAL AGONISTS	Sun Pharmaceutical Industries Limited (IN)	2023-03-15	—	—	EP	disclosed