SCHEMBL30423780

SCHEMBL30423780

CCc1cc(C#Cc2ccsc2)ccc1C#Cc1ccsc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.43
RAB9A P51151 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
HCRTR1 O43613 1/20 0.40
GRM5 P41594 7/20 0.40
POLB P06746 1/20 0.38
CYP2A6 P11509 1/20 0.38
DDR1 Q08345 1/20 0.36
DDR2 Q16832 1/20 0.36
FFAR1 O14842 1/20 0.35
IKBKB O14920 1/20 0.35
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
UBLCP1 Q8WVY7 1/20 0.32
BACE1 P56817 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7994512 1.00 NPC1 (0.43) NPC1RAB9AMEN1KMT2AHCRTR1
SCHEMBL19065055 0.82 FFAR1 (0.48) NPC1RAB9AMEN1KMT2AHCRTR1
SCHEMBL19789974 0.76 FFAR1 (0.51) NPC1RAB9AMEN1KMT2AGRM5
SCHEMBL12891122 0.75 FFAR1 (0.40) FFAR1
SCHEMBL13621099 0.75 FFAR1 (0.40) FFAR1
SCHEMBL12910016 0.75 CYP2A6 (0.47) CYP2A6FFAR1
SCHEMBL27975746 0.73 CYP2A6 (0.44) NPC1RAB9AMEN1KMT2AHCRTR1
SCHEMBL22733866 0.72 CYP2A6 (0.59) NPC1RAB9AMEN1KMT2AHCRTR1
SCHEMBL12807152 0.71 FFAR1 (0.38) FFAR1
SCHEMBL13620852 0.70 FFAR1 (0.46) NPC1RAB9AMEN1KMT2AGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110073507-B Organic semiconductor composition, organic thin film, and organic thin film transistor 日本化药株式会社 2023-07-04 CN disclosed