Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 3/20 | 0.37 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12891122 | 0.94 | FFAR1 (0.40) | FFAR1FFAR4GRM4 | |
| SCHEMBL13621099 | 0.94 | FFAR1 (0.40) | FFAR1FFAR4GRM4 | |
| SCHEMBL19789974 | 0.92 | FFAR1 (0.51) | FFAR1FFAR4APPGRM5HNF4A | |
| SCHEMBL19789963 | 0.88 | FFAR1 (0.41) | FFAR1FFAR4APPGRM5NPC1 | |
| SCHEMBL19790043 | 0.86 | FFAR1 (0.36) | FFAR1 | |
| SCHEMBL13620959 | 0.82 | FFAR1 (0.34) | FFAR1MMP2MMP9 | |
| SCHEMBL19057289 | 0.81 | GABRA1 (0.36) | FFAR1HSD17B10 | |
| SCHEMBL23335247 | 0.80 | ALDH1A1 (0.43) | FFAR1SMN1; SMN2HTTALDH1A1MAPT | |
| SCHEMBL23335296 | 0.80 | TRPV4 (0.50) | FFAR1FFAR4 | |
| SCHEMBL12910016 | 0.77 | CYP2A6 (0.47) | FFAR1FFAR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143328-A2 | ON WIRE LITHOGRAPHY-BASED MOLECULAR TRANSPORT JUNCTIONS | NORTHWESTERN UNIVERSITY (US) | 2009-11-26 | — | — | WO | disclosed |