Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24253956 | 1.00 | EP300 (0.32) | EP300TPH1 | |
| SCHEMBL24253749 | 0.83 | TPH1 (0.38) | TPH1 | |
| SCHEMBL30423951 | 0.83 | TPH1 (0.38) | TPH1 | |
| SCHEMBL30423914 | 0.83 | PDE10A (0.37) | EP300TPH1 | |
| SCHEMBL24253951 | 0.83 | PDE10A (0.37) | EP300TPH1 | |
| SCHEMBL24253877 | 0.82 | TPH1 (0.38) | TPH1 | |
| SCHEMBL30494515 | 0.82 | TPH1 (0.38) | TPH1 | |
| SCHEMBL30423993 | 0.81 | TPH1 (0.34) | EP300TPH1 | |
| SCHEMBL30423590 | 0.81 | TPH1 (0.32) | EP300TPH1 | |
| SCHEMBL30424374 | 0.81 | TPH1 (0.32) | TPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196478-A1 | HETEROARYL SUBSTITUTED SPIROPIPERIDINYL DERIVATIVES AND PHARMACEUTICAL USES THEREOF | Novartis AG (CH) | 2023-06-21 | — | — | EP | claimed |
| CN-116157404-A | Heteroaryl substituted spiropiperidinyl derivatives and pharmaceutical uses thereof | 诺华股份有限公司 | 2023-05-23 | — | — | CN | claimed |
| EP-4196478-A1 | HETEROARYL SUBSTITUTED SPIROPIPERIDINYL DERIVATIVES AND PHARMACEUTICAL USES THEREOF | Novartis AG (CH) | 2023-06-21 | — | — | EP | disclosed |
| CN-116157404-A | Heteroaryl substituted spiropiperidinyl derivatives and pharmaceutical uses thereof | 诺华股份有限公司 | 2023-05-23 | — | — | CN | disclosed |