Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24253919 | 1.00 | RAD51 (0.31) | RAD51 | |
| SCHEMBL24253921 | 0.91 | RAD51 (0.31) | RAD51 | |
| SCHEMBL30424173 | 0.91 | RAD51 (0.31) | RAD51 | |
| SCHEMBL30424618 | 0.89 | — | — | |
| SCHEMBL30423561 | 0.83 | DPP4 (0.36) | RAD51 | |
| SCHEMBL24253726 | 0.83 | DPP4 (0.36) | RAD51 | |
| SCHEMBL24253830 | 0.81 | AKT1S1 (0.36) | RAD51 | |
| SCHEMBL30423907 | 0.81 | AKT1S1 (0.36) | RAD51 | |
| SCHEMBL24253923 | 0.81 | RAD51 (0.33) | RAD51 | |
| SCHEMBL24253719 | 0.80 | RAD51 (0.31) | RAD51 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196478-A1 | HETEROARYL SUBSTITUTED SPIROPIPERIDINYL DERIVATIVES AND PHARMACEUTICAL USES THEREOF | Novartis AG (CH) | 2023-06-21 | — | — | EP | claimed |
| CN-116157404-A | Heteroaryl substituted spiropiperidinyl derivatives and pharmaceutical uses thereof | 诺华股份有限公司 | 2023-05-23 | — | — | CN | claimed |
| EP-4196478-A1 | HETEROARYL SUBSTITUTED SPIROPIPERIDINYL DERIVATIVES AND PHARMACEUTICAL USES THEREOF | Novartis AG (CH) | 2023-06-21 | — | — | EP | disclosed |
| CN-116157404-A | Heteroaryl substituted spiropiperidinyl derivatives and pharmaceutical uses thereof | 诺华股份有限公司 | 2023-05-23 | — | — | CN | disclosed |