Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | HRH2 | P25021 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20766385 | 0.91 | SIGMAR1 (0.73) | SIGMAR1SLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL13135282 | 0.89 | HPGD (0.57) | SIGMAR1HPGDTDP1 | |
| SCHEMBL17883819 | 0.84 | SIGMAR1 (0.53) | SIGMAR1SLC6A2SLC6A4SLC6A3HRH2 | |
| SCHEMBL9349447 | 0.84 | HRH3 (0.58) | SIGMAR1HRH2HRH1HRH3 | |
| SCHEMBL9592843 | 0.84 | HRH3 (0.58) | SIGMAR1HRH2HRH1HRH3 | |
| SCHEMBL25727760 | 0.84 | SIGMAR1 (0.64) | SIGMAR1SLC6A2SLC6A4SLC6A3HRH2 | |
| SCHEMBL11317277 | 0.83 | SIGMAR1 (0.60) | SIGMAR1SLC6A2SLC6A4SLC6A3HRH3 | |
| SCHEMBL11317274 | 0.83 | SIGMAR1 (0.60) | SIGMAR1SLC6A2SLC6A4SLC6A3HRH3 | |
| SCHEMBL9618520 | 0.83 | SIGMAR1 (0.63) | SIGMAR1SLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL14451132 | 0.82 | HPGD (0.52) | SIGMAR1KDM1AHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-20130155338-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-20 | — | — | US | disclosed |
| WO-2012025182-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-03-01 | — | — | WO | disclosed |