Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4472635 | 0.82 | CCNC (0.50) | CYP1A2HSD17B10CYP2C19MEN1KMT2A | |
| SCHEMBL4472628 | 0.82 | CCNC (0.50) | CYP1A2HSD17B10CYP2C19MEN1KMT2A | |
| SCHEMBL13473596 | 0.81 | ALDH1A1 (0.50) | HSD17B10RAB9APOLBMEN1KMT2A | |
| SCHEMBL30423635 | 0.81 | BACE1 (0.61) | CYP1A2HSD17B10CYP2C19NPC1RAB9A | |
| SCHEMBL29227737 | 0.81 | BACE1 (0.61) | CYP1A2HSD17B10CYP2C19NPC1RAB9A | |
| SCHEMBL2658196 | 0.81 | BACE1 (0.61) | CYP1A2HSD17B10CYP2C19NPC1RAB9A | |
| SCHEMBL2658197 | 0.81 | BACE1 (0.61) | CYP1A2HSD17B10CYP2C19NPC1RAB9A | |
| SCHEMBL28016713 | 0.80 | KDM4E (0.49) | HSD17B10NPC1RAB9APOLBMEN1 | |
| SCHEMBL30423841 | 0.79 | CYP1A2 (0.50) | CYP1A2HSD17B10CYP2C19NPC1RAB9A | |
| SCHEMBL29438041 | 0.78 | KDM4E (0.61) | HSD17B10RAB9APOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143602-B | Indenone and indazolone derivatives with antioxidant activity, and synthetic method and application thereof | 西南大学 | 2024-10-22 | — | — | CN | disclosed |
| CN-116554104-A | Indenone and indazolone derivatives with antioxidant activity, and synthetic method and application thereof | 西南大学 | 2023-08-08 | — | — | CN | disclosed |
| CN-116143602-A | Indenone and indazolone derivatives with antioxidant activity, and synthetic method and application thereof | 西南大学 | 2023-05-23 | — | — | CN | disclosed |