Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25203706 | 1.00 | BRD4 (0.36) | BRD4CA12CA1CA2CA9 | |
| SCHEMBL25202803 | 0.87 | NSD2 (0.37) | BRD4CA12CA1CA2CA9 | |
| SCHEMBL30424251 | 0.87 | NSD2 (0.37) | BRD4CA12CA1CA2CA9 | |
| SCHEMBL30424238 | 0.85 | TEAD1 (0.42) | BRD4HDAC10HDAC6SCN9AL3MBTL1 | |
| SCHEMBL25243401 | 0.85 | TEAD1 (0.42) | BRD4HDAC10HDAC6SCN9AL3MBTL1 | |
| SCHEMBL25249750 | 0.85 | P2RX7 (0.34) | HDAC6SCN9ACYP2D6POLBCYP1A2 | |
| SCHEMBL25751802 | 0.79 | TEAD1 (0.43) | BRD4CA12CA1CA2CA9 | |
| SCHEMBL25751810 | 0.78 | TEAD1 (0.55) | BRD4CA12CA1CA2CA9 | |
| SCHEMBL25751808 | 0.77 | TEAD1 (0.41) | BRD4CA12CA1CA2CA9 | |
| SCHEMBL25751804 | 0.76 | TEAD1 (0.41) | BRD4CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302411-A | Therapeutic indazole compounds and methods of use thereof for the treatment of cancer | 基因泰克公司 | 2024-07-05 | — | — | CN | disclosed |