Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18044835 | 1.00 | ENPP2 (0.52) | ENPP2HDAC6HDAC1HDAC8CHRM2 | |
| SCHEMBL16742434 | 1.00 | ENPP2 (0.52) | ENPP2HDAC6HDAC1HDAC8CHRM2 | |
| SCHEMBL16742433 | 1.00 | ENPP2 (0.52) | ENPP2HDAC6HDAC1HDAC8CHRM2 | |
| SCHEMBL16750193 | 0.92 | ENPP2 (0.49) | ENPP2HDAC6HDAC1HDAC8HDAC3 | |
| SCHEMBL16750309 | 0.91 | HDAC6 (0.50) | ENPP2HDAC6HDAC1HDAC8HDAC3 | |
| SCHEMBL16750333 | 0.87 | HDAC6 (0.47) | ENPP2HDAC6HDAC1HDAC8HDAC3 | |
| SCHEMBL18070799 | 0.87 | ENPP2 (0.50) | ENPP2HDAC6HDAC1HDAC8TBXA2R | |
| SCHEMBL16750311 | 0.87 | ENPP2 (0.50) | ENPP2HDAC6HDAC1HDAC8TBXA2R | |
| SCHEMBL18044815 | 0.87 | HDAC6 (0.48) | ENPP2HDAC6HDAC1HDAC8CHRM2 | |
| SCHEMBL16750266 | 0.87 | HDAC6 (0.48) | ENPP2HDAC6HDAC1HDAC8CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116059203-A | Autotaxin inhibitors and uses thereof | 赛博治疗有限责任公司 | 2023-05-05 | — | — | CN | disclosed |