SCHEMBL30427404

SCHEMBL30427404

CSCCC(NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCC(N)=O)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(Cc1ccccc1)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C(N)Cc1c[nH]cn1)C(C)C)C(C)O)C(N)=O

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CRHR1 P34998 1/20 0.66
▸ CRHR2 Q13324 1/20 0.66
▸ CALCR P30988 3/20 0.65
▸ GLP1R P43220 14/20 0.64
▸ SCTR P47872 1/20 0.62
▸ CCKBR P32239 1/20 0.61
▸ GCGR P47871 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29692863 0.94 GLP1R (0.69) GLP1RSCTRGCGR
SCHEMBL30184797 0.94 GLP1R (0.69) GLP1RSCTRGCGR
SCHEMBL29692881 0.94 GLP1R (0.69) GLP1RSCTRGCGR
SCHEMBL30076320 0.94 GLP1R (0.69) GLP1RSCTRGCGR
SCHEMBL29356509 0.94 GLP1R (0.69) GLP1RSCTRGCGR
SCHEMBL29692888 0.94 GLP1R (0.69) GLP1RSCTRGCGR
SCHEMBL29692871 0.94 GLP1R (0.69) GLP1RSCTRGCGR
SCHEMBL31291000 0.94 GLP1R (0.69) GLP1RSCTRGCGR
SCHEMBL30053976 0.94 GLP1R (0.69) GLP1RSCTRGCGR
SCHEMBL30148474 0.94 GLP1R (0.67) CALCRGLP1RSCTRGCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12358980-B2 Compositions and methods for anti-PACAP antibodies CEPHALON LLC (US) 2025-07-15 — — US disclosed
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME LONGEVITY BIOTECH, INC. 2024-11-14 — — US disclosed
CN-118556079-A Compositions and methods of anti-PACAP antibodies 瑟法隆有限责任公司 2024-08-27 — — CN disclosed
US-20230212281-A1 COMPOSITIONS AND METHODS FOR ANTI-PACAP ANTIBODIES CEPHALON LLC 2023-07-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME SCTR, GIPR, APLNR CRHR1 195/4885CRHR2 386/4885CALCR 118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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