Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30427246 | 0.82 | PDE10A (0.45) | PDE10AMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL25190170 | 0.82 | GRM4 (0.36) | — | |
| SCHEMBL15401351 | 0.75 | BTK (0.55) | PDE10AMAP4K4JAK3BTKKDM4D | |
| SCHEMBL24541862 | 0.74 | PDE10A (0.43) | PDE10AMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL29952159 | 0.72 | PIM1 (0.44) | PDE10AMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL4476430 | 0.72 | PDE10A (0.46) | PDE10AMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL29954510 | 0.72 | PIM1 (0.55) | PDE10AMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL24951335 | 0.71 | PDE10A (0.56) | PDE10AMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL30819455 | 0.71 | PDE10A (0.56) | PDE10AMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL30202103 | 0.71 | PDE10A (0.56) | PDE10AMAP4K4CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024232597-A1 | 4-CHROMANONE COMPOUNDS THAT DEGRADE WDR5 AND USES THEREOF | 엘젠테라퓨틱스 주식회사 | 2024-11-14 | — | — | WO | disclosed |
| WO-2023090829-A1 | LOW-MOLECULAR-WEIGHT COMPOUND FOR REGULATING MLL1-WDR5 INTERACTION AND USE THEREOF | 엘젠테라퓨틱스 주식회사 | 2023-05-25 | — | — | WO | disclosed |