Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12694575 | 0.90 | PIM1 (0.52) | PIM1PIM3PIM2KMT2AL3MBTL1 | |
| SCHEMBL29951880 | 0.90 | PIM1 (0.52) | PIM1PIM3PIM2KMT2AL3MBTL1 | |
| SCHEMBL31073157 | 0.87 | CKS1B (0.49) | PIM1PIM3PIM2KMT2AL3MBTL1 | |
| SCHEMBL29957145 | 0.85 | KMT2A (0.42) | PIM1PIM3PIM2KMT2AL3MBTL1 | |
| SCHEMBL31142648 | 0.85 | EPHX2 (0.44) | PIM1PIM3PIM2KMT2AL3MBTL1 | |
| SCHEMBL31142639 | 0.85 | EPHX2 (0.44) | PIM1PIM3PIM2KMT2AL3MBTL1 | |
| SCHEMBL29840412 | 0.84 | NPC1 (0.44) | PIM1PIM3PIM2KMT2AL3MBTL1 | |
| SCHEMBL20806445 | 0.83 | KMT2A (0.52) | PIM1PIM3PIM2KMT2AL3MBTL1 | |
| SCHEMBL30932001 | 0.81 | CTSK (0.43) | PIM1PIM3PIM2KMT2AL3MBTL1 | |
| SCHEMBL17315459 | 0.80 | CA2 (0.51) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |