Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7349980 | 0.78 | SLC6A4 (0.41) | SLC6A4HTR2ASLC6A2ADRB2HTR1A | |
| SCHEMBL2761385 | 0.77 | SLC6A4 (0.43) | SLC6A4HTR2ASLC6A2ADRB2HTR1A | |
| SCHEMBL2892626 | 0.77 | SLC6A2 (0.36) | MEN1KMT2ASLC6A4HTR2ASLC6A2 | |
| SCHEMBL7216614 | 0.76 | SLC6A4 (0.44) | SLC6A4HTR2ASLC6A2ADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL6310841 | 0.76 | SLC6A2 (0.46) | MEN1KMT2ASLC6A4HTR2ASLC6A2 | |
| SCHEMBL5116224 | 0.75 | SLC6A4 (0.43) | SLC6A4HTR2ASLC6A2ADRB2HTR1A | |
| SCHEMBL6008849 | 0.75 | SLC6A2 (0.41) | MEN1KMT2ASLC6A4HTR2ASLC6A2 | |
| SCHEMBL6978725 | 0.73 | GFER (0.44) | SLC6A4HTR2ASLC6A2ADRB2HTR1A | |
| SCHEMBL6941071 | 0.72 | SLC6A4 (0.46) | SLC6A4HTR2ASLC6A2ADRB2HTR1A | |
| SCHEMBL9385927 | 0.72 | MEN1 (0.48) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111051309-B | Triazolotriazine derivatives useful as A2A receptor antagonists | 浙江春禾医药科技有限公司 | 2023-05-26 | — | — | CN | disclosed |