Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | GHSR | Q92847 | 4/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4849847 | 0.89 | MTNR1B (0.45) | MTNR1BDRD2GHSRMTNR1APRMT5 | |
| SCHEMBL4839514 | 0.86 | MTNR1B (0.46) | MTNR1BDRD2GHSRPRMT5WDR77 | |
| SCHEMBL30429107 | 0.86 | MTNR1B (0.46) | MTNR1BDRD2GHSRPRMT5WDR77 | |
| SCHEMBL30645340 | 0.86 | MTNR1B (0.46) | MTNR1BDRD2GHSRPRMT5WDR77 | |
| SCHEMBL4833087 | 0.85 | MTNR1B (0.48) | MTNR1BDRD2GHSRMTNR1APRMT5 | |
| SCHEMBL31032732 | 0.85 | MTNR1B (0.46) | MTNR1BDRD2GHSRPRMT5WDR77 | |
| SCHEMBL11929926 | 0.85 | MTNR1B (0.47) | MTNR1BDRD2GHSRMTNR1APRMT5 | |
| SCHEMBL30428513 | 0.84 | MTNR1B (0.45) | MTNR1BDRD2GHSRPRMT5WDR77 | |
| SCHEMBL18066403 | 0.83 | MEN1 (0.50) | MTNR1BDRD2GHSRPRMT5WDR77 | |
| SCHEMBL30558539 | 0.83 | MEN1 (0.50) | MTNR1BDRD2GHSRPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111511750-B | Macrocyclic derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2023-06-13 | — | — | CN | disclosed |