SCHEMBL3042893

SCHEMBL3042893

C#Cc1cc2c3c(ccc4c5ccc6c7c(ccc(c1c34)c75)C(=O)N(C(CC)CC)C6=O)C(=O)N(C(CC)CC)C2=O

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TERT O14746 8/20 0.38
STAT3 P40763 1/20 0.34
HIF1A Q16665 1/20 0.34
PIN1 Q13526 1/20 0.30
PIN4 Q9Y237 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13087557 0.88 TERT (0.33) TERTSTAT3HIF1A
SCHEMBL15188871 0.85 TERT (0.36) TERTSTAT3HIF1A
SCHEMBL13097781 0.85 TERT (0.34) TERTSTAT3HIF1A
SCHEMBL13754696 0.85 TERT (0.34) TERTSTAT3HIF1APIN1PIN4
SCHEMBL17514376 0.84 TERT (0.36) TERTSTAT3HIF1APIN1PIN4
SCHEMBL13087178 0.83 TERT (0.35) TERTSTAT3HIF1A
SCHEMBL19237466 0.83 TERT (0.30) TERT
SCHEMBL19242893 0.83 TERT (0.33) TERT
SCHEMBL305590 0.82 TERT (0.47) TERTSTAT3HIF1APIN1PIN4
SCHEMBL30195004 0.82 TERT (0.47) TERTSTAT3HIF1APIN1PIN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150152106-A1 SELECTIVE BROMINATION OF PERYLENE DIIMIDES AND DERIVATIVES THEREOF UNDER MILD CONDITIONS YEDA RESEARCH AND DEVELOPMENT CO.LTD (IL) 2015-06-04 US disclosed
US-20150152106-A1 SELECTIVE BROMINATION OF PERYLENE DIIMIDES AND DERIVATIVES THEREOF UNDER MILD CONDITIONS YEDA RESEARCH AND DEVELOPMENT CO.LTD (IL) 2015-06-04 US disclosed
US-20150152106-A1 SELECTIVE BROMINATION OF PERYLENE DIIMIDES AND DERIVATIVES THEREOF UNDER MILD CONDITIONS YEDA RESEARCH AND DEVELOPMENT CO.LTD (IL) 2015-06-04 US disclosed
US-8859772-B2 Selective bromination of perylene diimides and derivatives thereof under mild conditions YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2014-10-14 US disclosed
US-8859772-B2 Selective bromination of perylene diimides and derivatives thereof under mild conditions YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2014-10-14 US disclosed
US-8859772-B2 Selective bromination of perylene diimides and derivatives thereof under mild conditions YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2014-10-14 US disclosed
EP-2626359-B1 PERYLENE DIIMIDES YEDA RES & DEV (IL) 2014-08-06 EP disclosed
US-20130231481-A1 SELECTIVE BROMINATION OF PERYLENE DIIMIDES AND DERIVATIVES THEREOF UNDER MILD CONDITIONS YED RESEARCH AND DEVELOPMENT CO.LTD (IL) 2013-09-05 US disclosed
US-20130231481-A1 SELECTIVE BROMINATION OF PERYLENE DIIMIDES AND DERIVATIVES THEREOF UNDER MILD CONDITIONS YED RESEARCH AND DEVELOPMENT CO.LTD (IL) 2013-09-05 US disclosed
US-20130231481-A1 SELECTIVE BROMINATION OF PERYLENE DIIMIDES AND DERIVATIVES THEREOF UNDER MILD CONDITIONS YED RESEARCH AND DEVELOPMENT CO.LTD (IL) 2013-09-05 US disclosed
EP-2626359-A1 Perylene diimides Yeda Research and Development Co. Ltd. (IL) 2013-08-14 EP disclosed
EP-2155741-B1 SELECTIVE BROMINATION OF PERYLENE DIIMIDES AND DERIVATIVES THEREOF UNDER MILD CONDITIONS YEDA RES & DEV (IL) 2013-06-26 EP disclosed
US-8399670-B2 Selective bromination of perylene diimides and derivatives thereof under mild conditions YEDA RESEARCH AND DEVELOPMENT CO.LTD (IL) 2013-03-19 US disclosed
US-8399670-B2 Selective bromination of perylene diimides and derivatives thereof under mild conditions YEDA RESEARCH AND DEVELOPMENT CO.LTD (IL) 2013-03-19 US disclosed
US-8399670-B2 Selective bromination of perylene diimides and derivatives thereof under mild conditions YEDA RESEARCH AND DEVELOPMENT CO.LTD (IL) 2013-03-19 US disclosed
US-20100261901-A1 SELECTIVE BROMINATION OF PERYLENE DIIMIDES AND DERIVATIVES THEREOF UNDER MILD CONDITIONS YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 2010-10-14 US disclosed
US-20100261901-A1 SELECTIVE BROMINATION OF PERYLENE DIIMIDES AND DERIVATIVES THEREOF UNDER MILD CONDITIONS YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 2010-10-14 US disclosed
US-20100261901-A1 SELECTIVE BROMINATION OF PERYLENE DIIMIDES AND DERIVATIVES THEREOF UNDER MILD CONDITIONS YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 2010-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130231481-A1 SELECTIVE BROMINATION OF PERYLENE DIIMIDES AND DERIVATIVES THEREOF UNDER MILD CONDITIONS BAZ2A, BAZ2B, BRD2 TERT 1416/4885STAT3 3978/4885HIF1A 4430/4885
US-20150152106-A1 SELECTIVE BROMINATION OF PERYLENE DIIMIDES AND DERIVATIVES THEREOF UNDER MILD CONDITIONS BAZ2A, BAZ2B, BRD2 TERT 1416/4885STAT3 3978/4885HIF1A 4430/4885
US-20100261901-A1 SELECTIVE BROMINATION OF PERYLENE DIIMIDES AND DERIVATIVES THEREOF UNDER MILD CONDITIONS BAZ2A, BAZ2B, BRD2 TERT 1416/4885STAT3 3978/4885HIF1A 4430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.