Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 20/20 | 0.56 |
| ▸ | WDR77 | Q9BQA1 | 15/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25208948 | 0.97 | PRMT5 (0.58) | PRMT5WDR77 | |
| SCHEMBL25221624 | 0.87 | PRMT5 (0.58) | PRMT5WDR77 | |
| SCHEMBL30833175 | 0.85 | PRMT5 (0.43) | PRMT5WDR77 | |
| SCHEMBL25263666 | 0.83 | PRMT5 (0.79) | PRMT5WDR77 | |
| SCHEMBL29280294 | 0.83 | PRMT5 (0.63) | PRMT5WDR77 | |
| SCHEMBL23087822 | 0.81 | PRMT5 (0.59) | PRMT5WDR77 | |
| SCHEMBL29735261 | 0.81 | PRMT5 (0.59) | PRMT5WDR77 | |
| SCHEMBL25267553 | 0.80 | PRMT5 (0.51) | PRMT5WDR77 | |
| SCHEMBL31222761 | 0.79 | PRMT5 (0.78) | PRMT5WDR77 | |
| SCHEMBL25580094 | 0.79 | PRMT5 (0.78) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098439-A1 | PYRAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 上海和誉生物医药科技有限公司 | 2023-06-08 | — | — | WO | disclosed |