SCHEMBL30429732

CC[C@H](C)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCSC)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	7/20	0.51

▸	BACE2	Q9Y5Z0	3/20	0.48

▸	ENPEP	Q07075	5/20	0.47

▸	OPRD1	P41143	1/20	0.45

▸	FNTA	P49354	2/20	0.44

▸	FNTB	P49356	2/20	0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29985919	0.95	BACE1 (0.51)	BACE1BACE2ENPEPOPRD1
SCHEMBL31510399	0.95	BACE1 (0.54)	BACE1BACE2OPRD1FNTAFNTB
SCHEMBL29972923	0.88	NAALAD2 (0.53)	BACE1BACE2ENPEP
SCHEMBL30503367	0.88	BACE1 (0.55)	BACE1BACE2OPRD1
SCHEMBL31510397	0.87	BACE1 (0.60)	BACE1BACE2FNTAFNTB
SCHEMBL31039957	0.87	FNTA (0.52)	OPRD1FNTAFNTB
SCHEMBL29655823	0.86	ENPEP (0.52)	BACE1BACE2ENPEP
SCHEMBL30501948	0.86	BACE1 (0.57)	BACE1BACE2OPRD1
SCHEMBL29430202	0.86	NAALAD2 (0.56)	BACE1FNTAFNTB
SCHEMBL29630512	0.85	BACE1 (0.50)	BACE1BACE2ENPEPOPRD1FNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-111108116-B	Retroviral vectors	牛津遗传学有限公司	2024-03-26	—	—	CN	disclosed
US-11667929-B2	Retroviral vectors	Oxford Genetics Limited (GB)	2023-06-06	—	—	US	disclosed