Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.55 |
| ▸ | MGLL | Q99685 | 5/20 | 0.50 |
| ▸ | FAAH | O00519 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18932194 | 1.00 | PTGS1 (0.55) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL23652024 | 0.94 | PTGS1 (0.46) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL19708967 | 0.91 | PTGS1 (0.49) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL17721377 | 0.88 | PTGS1 (0.58) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL23506482 | 0.88 | PTGS1 (0.41) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL12965566 | 0.85 | PTGS1 (0.51) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL21697887 | 0.85 | PTGS1 (0.51) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL19514146 | 0.85 | PTGS1 (0.55) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL15189321 | 0.85 | PTGS1 (0.55) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL14660025 | 0.84 | PTGS1 (0.58) | PTGS1PTGS2MGLLFAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116209476-A | Antifolate linker-drug and antibody-drug conjugates | 拜奥迪斯私人有限公司 | 2023-06-02 | — | — | CN | disclosed |