Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.49 |
| ▸ | MGLL | Q99685 | 5/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18932194 | 0.91 | PTGS1 (0.55) | PTGS1PTGS2MGLLFAAHSMN1; SMN2 | |
| SCHEMBL30433145 | 0.91 | PTGS1 (0.55) | PTGS1PTGS2MGLLFAAHSMN1; SMN2 | |
| SCHEMBL19257599 | 0.86 | PTGS1 (0.48) | PTGS1PTGS2MGLLFAAHSMN1; SMN2 | |
| SCHEMBL24383401 | 0.85 | PTGS1 (0.45) | PTGS1PTGS2MGLLFAAHSMN1; SMN2 | |
| SCHEMBL23652024 | 0.85 | PTGS1 (0.46) | PTGS1PTGS2MGLLFAAHSMN1; SMN2 | |
| SCHEMBL25748815 | 0.83 | PTGS1 (0.50) | PTGS1PTGS2MGLLFAAHSMN1; SMN2 | |
| SCHEMBL25748817 | 0.83 | PTGS1 (0.50) | PTGS1PTGS2MGLLFAAHSMN1; SMN2 | |
| SCHEMBL22267883 | 0.83 | PTGS1 (0.45) | PTGS1PTGS2MGLLFAAHSMN1; SMN2 | |
| SCHEMBL14962680 | 0.83 | PTGS1 (0.53) | PTGS1PTGS2MGLLFAAHSMN1; SMN2 | |
| SCHEMBL18932354 | 0.83 | PTGS1 (0.42) | PTGS1PTGS2MGLLFAAHSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017214456-A1 | ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES | ABBVIE INC. (US) | 2017-12-14 | — | — | WO | disclosed |