Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29027824 | 0.80 | CTSS (0.44) | MEN1KMT2ACTSSCTSKBACE1 | |
| SCHEMBL29027813 | 0.80 | CTSS (0.44) | MEN1KMT2ACTSSCTSKBACE1 | |
| SCHEMBL24343449 | 0.80 | CTSS (0.44) | MEN1KMT2ACTSSCTSKBACE1 | |
| SCHEMBL399012 | 0.77 | GAA (0.50) | MEN1KMT2AGAAHSD17B10KDM4E | |
| SCHEMBL22501367 | 0.76 | MEN1 (0.53) | MEN1KMT2ACTSSCTSKBACE1 | |
| SCHEMBL26347288 | 0.75 | MEN1 (0.52) | MEN1KMT2ACTSSCTSKBACE1 | |
| SCHEMBL31045240 | 0.75 | BACE1 (0.47) | MEN1KMT2ACTSSCTSKBACE1 | |
| SCHEMBL22815478 | 0.74 | MEN1 (0.56) | MEN1KMT2ACTSSCTSKBACE1 | |
| SCHEMBL19277932 | 0.74 | MEN1 (0.56) | MEN1KMT2ACTSSCTSKBACE1 | |
| SCHEMBL19391315 | 0.74 | MEN1 (0.56) | MEN1KMT2ACTSSCTSKBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116209476-A | Antifolate linker-drug and antibody-drug conjugates | 拜奥迪斯私人有限公司 | 2023-06-02 | — | — | CN | disclosed |