Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.84 |
| ▸ | MEN1 | O00255 | 2/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.84 |
| ▸ | RECQL | P46063 | 1/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.58 |
| ▸ | PDE5A | O76074 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28446530 | 0.95 | MEN1 (0.77) | MAPTMEN1KMT2ARECQLKDM4E | |
| SCHEMBL30435684 | 0.94 | MAPT (0.76) | MAPTMEN1KMT2ARECQLKDM4E | |
| SCHEMBL30435245 | 0.91 | MEN1 (0.71) | MAPTMEN1KMT2ARECQLKDM4E | |
| SCHEMBL28440914 | 0.90 | MEN1 (0.70) | MAPTMEN1KMT2ARECQLKDM4E | |
| SCHEMBL23052578 | 0.89 | MAPT (0.85) | MAPTMEN1KMT2ARECQLKDM4E | |
| SCHEMBL28442773 | 0.87 | MEN1 (0.66) | MAPTMEN1KMT2ARECQLKDM4E | |
| SCHEMBL30434922 | 0.86 | MEN1 (0.74) | MAPTMEN1KMT2ARECQLKDM4E | |
| SCHEMBL3313038 | 0.86 | RAB9A (0.74) | MAPTMEN1KMT2ARECQLKDM4E | |
| SCHEMBL30435353 | 0.85 | MEN1 (0.73) | MAPTMEN1KMT2ARECQLKDM4E | |
| SCHEMBL30435008 | 0.85 | MEN1 (0.72) | MAPTMEN1KMT2ARECQLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423374-B | Dihydropyrazole sulfonamide compound and preparation method and application thereof | 合肥工业大学 | 2023-03-21 | — | — | CN | disclosed |