Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL445410 | 1.00 | KMT2A (0.44) | KMT2AL3MBTL1MEN1MAPTGAA | |
| SCHEMBL14309698 | 0.88 | KMT2A (0.46) | KMT2AL3MBTL1MEN1MAPTGAA | |
| SCHEMBL1923555 | 0.84 | LCK (0.43) | KMT2AL3MBTL1MEN1MAPTGAA | |
| SCHEMBL30434727 | 0.84 | LCK (0.43) | KMT2AL3MBTL1MEN1MAPTGAA | |
| SCHEMBL30434880 | 0.84 | LCK (0.43) | KMT2AL3MBTL1MEN1MAPTGAA | |
| SCHEMBL6714580 | 0.84 | KMT2A (0.40) | KMT2AL3MBTL1MEN1MAPTGAA | |
| SCHEMBL6714575 | 0.79 | NPC1 (0.48) | KMT2AL3MBTL1MEN1MAPTALDH1A1 | |
| SCHEMBL14031772 | 0.76 | KMT2A (0.42) | KMT2AL3MBTL1MEN1MAPTGAA | |
| SCHEMBL30435330 | 0.75 | LMNA (0.42) | KMT2AL3MBTL1MEN1MAPTGAA | |
| SCHEMBL29036570 | 0.75 | LMNA (0.42) | KMT2AL3MBTL1MEN1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116925076-A | Nevirapine intermediate compound and preparation method and application thereof | 山东新时代药业有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-116813538-A | Nevirapine intermediate compound and preparation method thereof | 山东新时代药业有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116410129-A | Nevirapine intermediate compound | 山东新时代药业有限公司 | 2023-07-11 | — | — | CN | disclosed |