Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19900499 | 1.00 | TSHR (0.50) | TSHRNR1H4ALDH1A1LMNAMAPT | |
| SCHEMBL19899873 | 0.92 | NR1H4 (0.49) | TSHRNR1H4ALDH1A1LMNAMAPT | |
| SCHEMBL19899955 | 0.91 | TSHR (0.50) | TSHRNR1H4ALDH1A1LMNAMAPT | |
| SCHEMBL30438165 | 0.86 | MAPT (0.48) | TSHRNR1H4ALDH1A1LMNAMAPT | |
| SCHEMBL19900216 | 0.86 | MAPT (0.48) | TSHRNR1H4ALDH1A1LMNAMAPT | |
| SCHEMBL19899919 | 0.82 | NR1H4 (0.51) | TSHRNR1H4ALDH1A1LMNAMAPT | |
| SCHEMBL30437362 | 0.82 | TSHR (0.49) | TSHRNR1H4ALDH1A1LMNAMAPT | |
| SCHEMBL30437325 | 0.80 | NR1H4 (0.49) | TSHRNR1H4ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL19900545 | 0.80 | NR1H4 (0.49) | TSHRNR1H4ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL19899881 | 0.80 | MAPT (0.50) | TSHRNR1H4ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177783-B | Hormone receptor modulators for the treatment of metabolic conditions and disorders | 阿德利克斯股份有限公司 | 2023-06-06 | — | — | CN | disclosed |