Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19900216 | 1.00 | MAPT (0.48) | MAPTTP53NR1H4TSHRALDH1A1 | |
| SCHEMBL19899881 | 0.95 | MAPT (0.50) | MAPTTP53NR1H4TSHRALDH1A1 | |
| SCHEMBL19899955 | 0.86 | TSHR (0.50) | MAPTNR1H4TSHRALDH1A1GAA | |
| SCHEMBL19900499 | 0.86 | TSHR (0.50) | MAPTNR1H4TSHRALDH1A1GAA | |
| SCHEMBL30436699 | 0.86 | TSHR (0.50) | MAPTNR1H4TSHRALDH1A1GAA | |
| SCHEMBL21456723 | 0.83 | POLB (0.49) | MAPTTP53NR1H4TSHRALDH1A1 | |
| SCHEMBL19216545 | 0.80 | IDH1 (0.51) | MAPTTP53TSHRALDH1A1GAA | |
| SCHEMBL30437182 | 0.79 | NR1H4 (0.49) | MAPTTP53NR1H4TSHRALDH1A1 | |
| SCHEMBL19899941 | 0.79 | NR1H4 (0.49) | MAPTTP53NR1H4TSHRALDH1A1 | |
| SCHEMBL30437325 | 0.78 | NR1H4 (0.49) | NR1H4TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177783-B | Hormone receptor modulators for the treatment of metabolic conditions and disorders | 阿德利克斯股份有限公司 | 2023-06-06 | — | — | CN | disclosed |