SCHEMBL30436764

SCHEMBL30436764

N#Cc1ccc(Cl)c(C(=O)Nc2ccnc(-c3cccnc3)c2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPARG P37231 6/20 1.00
PDGFRB P09619 2/20 0.52
PDGFRA P16234 2/20 0.52
ABL1 P00519 1/20 0.52
BCR P11274 1/20 0.52
PRKCA P17252 1/20 0.52
ATR Q13535 1/20 0.52
CSF1R P07333 8/20 0.49
BRAF P15056 1/20 0.48
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
CYP11B1 P15538 1/20 0.46
CYP11B2 P19099 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21055968 1.00 PPARG (1.00) PPARGPDGFRBPDGFRAABL1BCR
SCHEMBL30436926 0.90 PPARG (0.82) PPARG
SCHEMBL21055970 0.90 PPARG (0.82) PPARG
SCHEMBL21055975 0.88 PPARG (0.80) PPARG
SCHEMBL30436545 0.88 PPARG (0.80) PPARG
SCHEMBL21056003 0.88 PPARG (0.78) PPARGPDGFRBPDGFRAABL1BCR
SCHEMBL30436387 0.88 PPARG (0.78) PPARGPDGFRBPDGFRAABL1BCR
SCHEMBL21055976 0.88 PPARG (0.81) PPARGPDGFRBPDGFRAABL1BCR
SCHEMBL30436599 0.88 PPARG (0.81) PPARGPDGFRBPDGFRAABL1BCR
SCHEMBL21061694 0.87 PPARG (0.75) PPARGPDGFRBPDGFRAABL1BCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111630030-B Novel benzamide derivatives as PPAR-gamma modulators 梅迪比奥法尔玛公司 2023-06-20 CN claimed
CN-111630030-B Novel benzamide derivatives as PPAR-gamma modulators 梅迪比奥法尔玛公司 2023-06-20 CN disclosed