Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL595530 | 1.00 | MAPT (0.51) | MAPTSMN1; SMN2RXFP1RAB9ATP53 | |
| SCHEMBL24975195 | 0.91 | MAPK1 (0.54) | MAPTSMN1; SMN2RXFP1RAB9ATP53 | |
| SCHEMBL29854270 | 0.91 | MAPK1 (0.54) | MAPTSMN1; SMN2RXFP1RAB9ATP53 | |
| SCHEMBL29598250 | 0.87 | MAPK1 (0.61) | MAPTSMN1; SMN2RXFP1RAB9ATP53 | |
| SCHEMBL30436940 | 0.84 | GABRG2 (0.53) | MAPTRAB9AKDM4ENPC1CA1 | |
| SCHEMBL21056008 | 0.84 | CA12 (0.50) | MAPTSMN1; SMN2RXFP1RAB9ATP53 | |
| SCHEMBL30436074 | 0.84 | CA12 (0.50) | MAPTSMN1; SMN2RXFP1RAB9ATP53 | |
| SCHEMBL2030945 | 0.84 | GABRG2 (0.53) | MAPTRAB9AKDM4ENPC1CA1 | |
| SCHEMBL7942053 | 0.83 | MAPK1 (0.53) | MAPTSMN1; SMN2RXFP1KDM4EMAPK1 | |
| SCHEMBL31145166 | 0.83 | TDP1 (0.59) | MAPTSMN1; SMN2RXFP1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111630030-B | Novel benzamide derivatives as PPAR-gamma modulators | 梅迪比奥法尔玛公司 | 2023-06-20 | — | — | CN | disclosed |