Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.77 |
| ▸ | GRM5 | P41594 | 7/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21056021 | 1.00 | PPARG (0.77) | PPARGGRM5PTPN1PTPN6PTPN11 | |
| SCHEMBL30435682 | 0.91 | PPARG (0.64) | PPARGGRM5PTPN1PTPN6PTPN11 | |
| SCHEMBL21056011 | 0.91 | PPARG (0.64) | PPARGGRM5PTPN1PTPN6PTPN11 | |
| SCHEMBL21055977 | 0.89 | PPARG (0.62) | PPARGGRM5LRRK2 | |
| SCHEMBL30437002 | 0.89 | PPARG (0.62) | PPARGGRM5LRRK2 | |
| SCHEMBL21055998 | 0.87 | PPARG (1.00) | PPARGGRM5LRRK2WNT3AGRM4 | |
| SCHEMBL30436494 | 0.87 | PPARG (1.00) | PPARGGRM5LRRK2WNT3AGRM4 | |
| SCHEMBL30436815 | 0.86 | PPARG (0.67) | PPARGGRM5MEN1KMT2ALRRK2 | |
| SCHEMBL21056004 | 0.86 | PPARG (0.67) | PPARGGRM5MEN1KMT2ALRRK2 | |
| SCHEMBL31171364 | 0.84 | GRM5 (0.61) | PPARGGRM5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111630030-B | Novel benzamide derivatives as PPAR-gamma modulators | 梅迪比奥法尔玛公司 | 2023-06-20 | — | — | CN | claimed |
| CN-111630030-B | Novel benzamide derivatives as PPAR-gamma modulators | 梅迪比奥法尔玛公司 | 2023-06-20 | — | — | CN | disclosed |