Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.62 |
| ▸ | GRM5 | P41594 | 6/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.50 |
| ▸ | ATR | Q13535 | 1/20 | 0.49 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | BCR | P11274 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 2/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21055977 | 1.00 | PPARG (0.62) | PPARGGRM5CYP11B2CYP11B1ATR | |
| SCHEMBL30436845 | 0.89 | PPARG (0.77) | PPARGGRM5LRRK2 | |
| SCHEMBL21056021 | 0.89 | PPARG (0.77) | PPARGGRM5LRRK2 | |
| SCHEMBL21055976 | 0.88 | PPARG (0.81) | PPARGCYP11B2CYP11B1ATRSGMS2 | |
| SCHEMBL30436387 | 0.88 | PPARG (0.78) | PPARGGRM5CYP11B2CYP11B1ATR | |
| SCHEMBL21056003 | 0.88 | PPARG (0.78) | PPARGGRM5CYP11B2CYP11B1ATR | |
| SCHEMBL30436599 | 0.88 | PPARG (0.81) | PPARGCYP11B2CYP11B1ATRSGMS2 | |
| SCHEMBL21056011 | 0.87 | PPARG (0.64) | PPARGGRM5 | |
| SCHEMBL30435682 | 0.87 | PPARG (0.64) | PPARGGRM5 | |
| SCHEMBL21056019 | 0.87 | GRM5 (0.67) | PPARGGRM5CYP11B2CYP11B1SGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111630030-B | Novel benzamide derivatives as PPAR-gamma modulators | 梅迪比奥法尔玛公司 | 2023-06-20 | — | — | CN | claimed |
| CN-111630030-B | Novel benzamide derivatives as PPAR-gamma modulators | 梅迪比奥法尔玛公司 | 2023-06-20 | — | — | CN | disclosed |