Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19900425 | 1.00 | MEN1 (0.53) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL449624 | 0.90 | MEN1 (0.57) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL15825184 | 0.87 | KMT2A (0.72) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL8050780 | 0.86 | MEN1 (0.55) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL19900206 | 0.85 | SRD5A1 (0.42) | ALDH1A1KDM4EMAPTHSD17B10METAP1 | |
| SCHEMBL8036213 | 0.85 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL14013291 | 0.85 | MAPT (0.53) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL2064320 | 0.85 | MEN1 (0.53) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL972021 | 0.84 | CYP24A1 (0.53) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL7290713 | 0.84 | CYP24A1 (0.53) | MEN1KMT2AALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177783-B | Hormone receptor modulators for the treatment of metabolic conditions and disorders | 阿德利克斯股份有限公司 | 2023-06-06 | — | — | CN | disclosed |