Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 6/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344388 | 0.86 | TDP1 (0.60) | TDP1L3MBTL1TSHRCASP6CES2 | |
| SCHEMBL17145186 | 0.86 | TDP1 (0.47) | TDP1L3MBTL1TSHRCES2CES1 | |
| SCHEMBL1585078 | 0.82 | TDP1 (0.64) | TDP1L3MBTL1TSHRCASP6CES2 | |
| SCHEMBL633629 | 0.82 | TDP1 (0.46) | TDP1L3MBTL1TSHRCASP6MAPT | |
| SCHEMBL28416779 | 0.81 | L3MBTL1 (0.43) | TDP1L3MBTL1TSHRCES2CES1 | |
| SCHEMBL12086987 | 0.81 | TDP1 (0.62) | TDP1L3MBTL1TSHRCASP6CES2 | |
| SCHEMBL29154301 | 0.81 | TDP1 (0.45) | TDP1L3MBTL1TSHRCASP6MAPT | |
| SCHEMBL2532517 | 0.79 | TDP1 (0.44) | TDP1L3MBTL1TSHRCASP6MAPT | |
| SCHEMBL18338921 | 0.79 | TDP1 (0.47) | TDP1L3MBTL1TSHRCASP6MAPT | |
| SCHEMBL18744866 | 0.79 | TDP1 (0.51) | TDP1L3MBTL1TSHRCASP6CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954810-A | Regulator of fused ring derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-118302427-A | Fused ring derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| WO-2023098880-A1 | FUSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 | 2023-06-08 | — | — | WO | disclosed |