Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 19/20 | 0.79 |
| ▸ | THRA | P10827 | 16/20 | 0.79 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.59 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | ASPH | Q12797 | 1/20 | 0.59 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.59 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27433223 | 1.00 | THRB (0.79) | THRBTHRAEGLN1BBOX1SLC6A2 | |
| SCHEMBL30438379 | 0.91 | THRB (0.79) | THRBTHRAEGLN1BBOX1SLC6A2 | |
| SCHEMBL27433426 | 0.91 | THRB (0.79) | THRBTHRAEGLN1BBOX1SLC6A2 | |
| SCHEMBL27433567 | 0.89 | THRB (0.79) | THRBTHRAEGLN1BBOX1SLC6A2 | |
| SCHEMBL30438356 | 0.89 | THRB (0.89) | THRBTHRAEGLN1BBOX1SLC6A2 | |
| SCHEMBL27434113 | 0.89 | THRB (0.89) | THRBTHRAEGLN1BBOX1SLC6A2 | |
| SCHEMBL27433227 | 0.89 | THRB (0.96) | THRBTHRAEGLN1BBOX1SLC6A2 | |
| SCHEMBL27433220 | 0.89 | THRB (1.00) | THRBTHRAEGLN1BBOX1SLC6A2 | |
| SCHEMBL27433213 | 0.89 | THRB (1.00) | THRBTHRAEGLN1BBOX1SLC6A2 | |
| SCHEMBL30439021 | 0.86 | THRB (0.89) | THRBTHRAEGLN1BBOX1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115838354-B | Thyroid hormone receptor beta agonist compound and preparation method and application thereof | 中国科学院广州生物医药与健康研究院 | 2025-05-13 | — | — | CN | disclosed |
| CN-115838354-A | Thyroid hormone receptor beta agonist compound and preparation method and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-03-24 | — | — | CN | disclosed |