Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940084 | 0.80 | NPC1 (0.48) | EPHX1HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL20583847 | 0.77 | HSD17B10 (0.45) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL27044057 | 0.77 | HSD17B10 (0.45) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL23779175 | 0.77 | CA1 (0.57) | EPHX1HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL13295381 | 0.77 | CA1 (0.57) | EPHX1HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL14564148 | 0.77 | CA1 (0.57) | EPHX1HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL4336794 | 0.76 | SETD7 (0.52) | EPHX1HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL6874691 | 0.76 | EPHX1 (0.58) | EPHX1ALDH1A1MAPTUSP30NPC1 | |
| SCHEMBL13934773 | 0.76 | EPHX1 (0.58) | EPHX1ALDH1A1MAPTUSP30NPC1 | |
| SCHEMBL1896900 | 0.76 | EPHX1 (0.58) | EPHX1ALDH1A1MAPTUSP30NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116120243-A | aPKC inhibitor compound intermediate fragment, preparation method and application thereof | 都创(上海)医药科技股份有限公司 | 2023-05-16 | — | — | CN | disclosed |