SCHEMBL30438445

SCHEMBL30438445

O=C=Nc1ccccc1OC(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.42
ALDH1A1 P00352 3/20 0.40
HPGD P15428 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
GAA P10253 1/20 0.36
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
FFAR1 O14842 1/20 0.34
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
POLB P06746 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SLC22A12 Q96S37 1/20 0.33
KCNK3 O14649 1/20 0.33
KCNK9 Q9NPC2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12069 1.00 CYP3A4 (0.42) CYP3A4ALDH1A1HPGDTDP1GAA
SCHEMBL1967227 0.81 ALDH1A1 (0.43) CYP3A4ALDH1A1HPGDTDP1GAA
SCHEMBL10585108 0.80 ALDH1A1 (0.38) CYP3A4ALDH1A1HPGDTDP1KDM4E
SCHEMBL8594458 0.80 DDB1 (0.33) ALDH1A1SLC6A2SLC6A4CNR1CNR2
SCHEMBL14256865 0.79 ALDH1A1 (0.40) ALDH1A1GAARXRARXRBRXRG
SCHEMBL29369823 0.78 CYP3A4 (0.50) CYP3A4ALDH1A1HPGDTDP1
SCHEMBL3192927 0.78 ALDH1A1 (0.38) ALDH1A1GAARXRARXRBRXRG
SCHEMBL1356140 0.78 CYP3A4 (0.50) CYP3A4ALDH1A1HPGDTDP1
SCHEMBL10677796 0.76 CYP3A4 (0.38) CYP3A4ALDH1A1HPGDTDP1RXRA
SCHEMBL3958928 0.75 CYP3A4 (0.47) CYP3A4ALDH1A1HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431706-A Fatigue-resistant polyurethane elastomer and preparation method and application thereof 万勋科技(深圳)有限公司 2025-02-14 CN claimed
CN-119431706-A Fatigue-resistant polyurethane elastomer and preparation method and application thereof 万勋科技(深圳)有限公司 2025-02-14 CN disclosed
CN-112020525-B Adducts of amine catalysts for preparing isocyanurate polymers 科思创知识产权两合公司 2023-05-16 CN disclosed