Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 19/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20917135 | 1.00 | CACNA2D1 (0.51) | CACNA2D1SLC6A2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL20917088 | 0.88 | CACNA2D1 (0.52) | CACNA2D1SLC6A2 | |
| SCHEMBL20917105 | 0.88 | CACNA2D1 (0.49) | CACNA2D1SLC6A2SLC1A2SLC1A1 | |
| SCHEMBL20917044 | 0.88 | CACNA2D1 (0.51) | CACNA2D1SLC6A2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL20917077 | 0.84 | KCNK3 (0.54) | CACNA2D1 | |
| SCHEMBL20917140 | 0.83 | CACNA2D1 (0.50) | CACNA2D1SLC6A2 | |
| SCHEMBL20917082 | 0.82 | CACNA2D1 (0.50) | CACNA2D1SLC6A2 | |
| SCHEMBL30438634 | 0.82 | CACNA2D1 (0.50) | CACNA2D1SLC6A2 | |
| SCHEMBL21349106 | 0.76 | TAS1R3 (0.56) | — | |
| SCHEMBL20917092 | 0.76 | CACNA2D1 (0.56) | CACNA2D1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111225901-B | Propylamine derivatives for the treatment of pain and pain-related disorders | 埃斯特韦制药股份公司 | 2023-07-04 | — | — | CN | claimed |
| CN-111225901-B | Propylamine derivatives for the treatment of pain and pain-related disorders | 埃斯特韦制药股份公司 | 2023-07-04 | — | — | CN | disclosed |