SCHEMBL30438709

SCHEMBL30438709

CNCCC(Oc1cccc(N(C)C(=O)c2cccnc2)c1)c1cccs1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CACNA2D1 P54289 20/20 0.57
SLC6A2 P23975 9/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20917081 1.00 CACNA2D1 (0.57) CACNA2D1SLC6A2
SCHEMBL20917295 0.89 CACNA2D1 (0.56) CACNA2D1SLC6A2
SCHEMBL30438349 0.89 CACNA2D1 (0.56) CACNA2D1SLC6A2
SCHEMBL30438577 0.85 SLC6A4 (0.51) CACNA2D1SLC6A2
SCHEMBL20917311 0.85 SLC6A4 (0.51) CACNA2D1SLC6A2
SCHEMBL22714210 0.85 CACNA2D1 (0.58) CACNA2D1SLC6A2
SCHEMBL20917282 0.83 CACNA2D1 (0.55) CACNA2D1SLC6A2
SCHEMBL30438361 0.80 CACNA2D1 (0.59) CACNA2D1SLC6A2
SCHEMBL20917067 0.80 CACNA2D1 (0.59) CACNA2D1SLC6A2
SCHEMBL20917294 0.80 CACNA2D1 (0.54) CACNA2D1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111225901-B Propylamine derivatives for the treatment of pain and pain-related disorders 埃斯特韦制药股份公司 2023-07-04 CN claimed
CN-111225901-B Propylamine derivatives for the treatment of pain and pain-related disorders 埃斯特韦制药股份公司 2023-07-04 CN disclosed