SCHEMBL30438779

SCHEMBL30438779

Cc1cc(C(O)CNC(C)(C)C)ccc1O

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 5/20 0.68
HIF1A Q16665 4/20 0.68
TSHR P16473 3/20 0.68
ADRB1 P08588 3/20 0.68
CYP1A2 P05177 2/20 0.68
CYP2D6 P10635 2/20 0.68
NFKB1 P19838 1/20 0.68
TDP1 Q9NUW8 3/20 0.67
PMP22 Q01453 1/20 0.60
KMT2A Q03164 4/20 0.58
LMNA P02545 2/20 0.58
CASP7 P55210 2/20 0.58
CYP3A4 P08684 2/20 0.58
CYP2C9 P11712 1/20 0.58
MEN1 O00255 3/20 0.51
KDM4E B2RXH2 2/20 0.51
CASP1 P29466 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
BLM P54132 1/20 0.51
MAPT P10636 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6711726 1.00 ADRB2 (0.68) ADRB2HIF1ATSHRADRB1CYP1A2
Colterol SCHEMBL249585 0.87 ADRB2 (0.72) ADRB2HIF1ATSHRADRB1CYP1A2
Colterol SCHEMBL3220142 0.87 ADRB2 (0.72) ADRB2HIF1ATSHRADRB1CYP1A2
SCHEMBL28872990 0.87 ADRB2 (0.59) ADRB2HIF1ATSHRADRB1CYP1A2
Colterol SCHEMBL3207818 0.87 ADRB2 (0.72) ADRB2HIF1ATSHRADRB1CYP1A2
SCHEMBL11876645 0.83 ADRB2 (0.67) ADRB2HIF1ATSHRADRB1CYP1A2
SCHEMBL14456692 0.81 KDM4E (0.74) ADRB2HIF1ATSHRADRB1CYP1A2
SCHEMBL16208744 0.81 KDM4E (0.74) ADRB2HIF1ATSHRADRB1CYP1A2
Albuterol SCHEMBL122805 0.81 ADRB2 (1.00) ADRB2HIF1ATSHRADRB1CYP1A2
Albuterol SCHEMBL121596 0.81 ADRB2 (1.00) ADRB2HIF1ATSHRADRB1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111721845-B Synchronous detection method for five related substances of compound ipratropium bromide solution for inhalation 鲁南制药集团股份有限公司 2023-08-15 CN claimed
CN-111721845-B Synchronous detection method for five related substances of compound ipratropium bromide solution for inhalation 鲁南制药集团股份有限公司 2023-08-15 CN disclosed
CN-112979480-B Preparation method and application of salbutamol impurity 上海医药集团(本溪)北方药业有限公司 2023-05-16 CN disclosed
CN-112979480-B Preparation method and application of salbutamol impurity 上海医药集团(本溪)北方药业有限公司 2023-05-16 CN disclosed