SCHEMBL304391

SCHEMBL304391

COC(=O)N1CCCCC1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
POLB P06746 1/20 0.50
USP2 O75604 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.44
HSD11B1 P28845 1/20 0.44
CHRNB2 P17787 1/20 0.43
CHRNB4 P30926 1/20 0.43
CHRNA3 P32297 1/20 0.43
CHRNA4 P43681 1/20 0.43
TSHR P16473 2/20 0.43
MAPT P10636 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HPGD P15428 1/20 0.43
CYP2D6 P10635 1/20 0.43
NPC1 O15118 1/20 0.43
HTT P42858 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16512381 1.00 ALDH1A1 (0.50) ALDH1A1POLBUSP2CYP1A2CYP2C9
SCHEMBL14827284 1.00 ALDH1A1 (0.50) ALDH1A1POLBUSP2CYP1A2CYP2C9
SCHEMBL3316653 1.00 ALDH1A1 (0.50) ALDH1A1POLBUSP2CYP1A2CYP2C9
SCHEMBL12481132 1.00 ALDH1A1 (0.50) ALDH1A1POLBUSP2CYP1A2CYP2C9
SCHEMBL9987783 1.00 ALDH1A1 (0.50) ALDH1A1POLBUSP2CYP1A2CYP2C9
Hydrochloric Acid SCHEMBL3575914 0.97 ALDH1A1 (0.48) ALDH1A1POLBUSP2CYP1A2CYP2C9
Bromide SCHEMBL22412595 0.97 ALDH1A1 (0.48) ALDH1A1POLBUSP2CYP1A2CYP2C9
Methyl Alcohol SCHEMBL11559156 0.97 ALDH1A1 (0.48) ALDH1A1POLBUSP2CYP1A2CYP2C9
SCHEMBL2263812 0.97
Bromide SCHEMBL19839447 0.95 CYP1A2 (0.48) ALDH1A1POLBUSP2CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 722 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118541362-A Pyridazinylamino derivatives as ALK5 inhibitors 奇斯药制品公司 2024-08-23 CN claimed
CN-111727191-B Substituted azetidine dihydro-thienopyridines and their use as phosphodiesterase inhibitors 联合疗法公司 2024-01-05 CN claimed
CN-116964048-A Bicyclic tetrahydroazepine derivatives for the treatment of cancer 豪夫迈·罗氏有限公司 2023-10-27 CN claimed
CN-113649055-B Catalyst for selective hydrogenation of methyl picolinate and preparation method and application thereof 湖北大学 2023-03-24 CN claimed
CN-115819328-A Memantine urea derivative, preparation method thereof and application thereof in preparing medicine for treating soluble epoxide hydrolase mediated diseases 沈阳药科大学 2023-03-21 CN claimed
EP-4021895-A1 NOVEL QUINAZOLINE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE F. Hoffmann-La Roche AG (CH) 2022-07-06 EP claimed
CN-114585619-A alpha-D-galactopyranoside derivatives 爱杜西亚药品有限公司 2022-06-03 CN claimed
CN-114478360-A Benzamide derivative and preparation method and application thereof 江苏海洋大学 2022-05-13 CN claimed
CN-114456176-A Pyrrolotriazine compounds as TAM inhibitors 因赛特公司 2022-05-10 CN claimed
CN-114144230-A Macrocyclic azolopyridine derivatives as EED and PRC2 modulators 弗尔康医疗公司 2022-03-04 CN claimed
CN-1333758-A Substituted bicyclic derivatives useful as anticancer agents PFIZER PROD INC (US) 2002-01-30 CN claimed
EP-1140895-A2 THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-10-10 EP claimed
WO-2000040576-A2 THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-07-13 WO claimed
EP-0775132-A1 (AZETIDIN-1-YLALKYL)LACTAMS AS TACHYKININ ANTAGONISTS Pfizer Limited (GB) 1997-05-28 EP claimed
US-5563129-A Hydroquinone derivatives and intermediates for production thereof TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-10-08 US claimed
US-5436359-A Hydroquinone derivatives and intermediates for production thereof TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-07-25 US claimed
US-5354913-A Chemical intermediates for drugs or drugs as thromboxane, prostaglandin antagonist, lipoxygenase enzyme inhibitor, antioxidants TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-10-11 US claimed
US-5304658-A Quinone derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-04-19 US claimed
EP-0171251-B2 QUINONE DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1992-12-23 EP claimed
EP-0171251-B1 QUINONE DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1990-06-27 EP claimed