Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | TRPC6 | Q9Y210 | 7/20 | 0.47 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 3/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21045678 | 1.00 | CHRM2 (0.51) | CHRM2CHRM1CHRM3TRPC6EIF2AK4 | |
| SCHEMBL26133835 | 0.85 | CHRM2 (0.51) | CHRM2CHRM1CHRM3EIF2AK4PREP | |
| SCHEMBL29656871 | 0.82 | CHRM2 (0.50) | CHRM2CHRM1CHRM3EIF2AK4PREP | |
| SCHEMBL22367044 | 0.80 | TRPC6 (0.48) | TRPC6 | |
| SCHEMBL15174527 | 0.80 | TRPC6 (0.58) | TRPC6GPR119 | |
| SCHEMBL30439726 | 0.80 | TRPC6 (0.58) | TRPC6GPR119 | |
| SCHEMBL22471554 | 0.80 | CHRM2 (0.56) | CHRM2CHRM1CHRM3PREPHSD11B1 | |
| SCHEMBL15378924 | 0.80 | CHRM2 (0.56) | CHRM2CHRM1CHRM3PREPHSD11B1 | |
| SCHEMBL18352270 | 0.78 | TRPC6 (0.53) | TRPC6 | |
| SCHEMBL12425428 | 0.78 | HDAC1 (0.55) | CHRM2CHRM1CHRM3PREPHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111527078-B | Pyridinecarbonyl derivatives and their therapeutic use as TRPC6 inhibitors | 勃林格殷格翰国际公司 | 2023-06-02 | — | — | CN | disclosed |