Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 8/20 | 0.59 |
| ▸ | RBP4 | P02753 | 10/20 | 0.38 |
| ▸ | TTR | P02766 | 7/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21045745 | 1.00 | TRPC6 (0.59) | TRPC6RBP4TTR | |
| SCHEMBL21045712 | 0.89 | TRPC6 (0.58) | TRPC6 | |
| SCHEMBL30439927 | 0.89 | TRPC6 (0.58) | TRPC6 | |
| SCHEMBL21045798 | 0.83 | TRPC6 (0.55) | TRPC6 | |
| SCHEMBL21045875 | 0.81 | TRPC6 (0.56) | TRPC6 | |
| SCHEMBL21045696 | 0.80 | TRPC6 (0.57) | TRPC6 | |
| SCHEMBL88281 | 0.78 | TRPC6 (0.49) | TRPC6 | |
| SCHEMBL26458560 | 0.76 | TRPC6 (0.83) | TRPC6 | |
| SCHEMBL26458562 | 0.76 | TRPC6 (0.83) | TRPC6 | |
| SCHEMBL21045779 | 0.76 | TRPC6 (0.56) | TRPC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111527078-B | Pyridinecarbonyl derivatives and their therapeutic use as TRPC6 inhibitors | 勃林格殷格翰国际公司 | 2023-06-02 | — | — | CN | disclosed |