Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30440233 | 0.83 | CA1 (0.40) | GAAL3MBTL1CA1CA2CA7 | |
| SCHEMBL30440112 | 0.76 | MEN1 (0.39) | CTSKCTSLCTSSCTSBHTT | |
| SCHEMBL3469151 | 0.73 | CA1 (0.46) | GAAL3MBTL1CA1CA2CA7 | |
| SCHEMBL6791378 | 0.73 | CA1 (0.46) | GAAL3MBTL1CA1CA2CA7 | |
| SCHEMBL28953786 | 0.73 | CA1 (0.46) | GAAL3MBTL1CA1CA2CA7 | |
| SCHEMBL13617288 | 0.73 | CA1 (0.46) | GAAL3MBTL1CA1CA2CA7 | |
| SCHEMBL8270799 | 0.73 | CA1 (0.46) | GAAL3MBTL1CA1CA2CA7 | |
| SCHEMBL13694102 | 0.73 | CA1 (0.46) | GAAL3MBTL1CA1CA2CA7 | |
| SCHEMBL12420412 | 0.73 | GAA (0.35) | GAAL3MBTL1CA1CA2CA7 | |
| SCHEMBL10681261 | 0.70 | CA1 (0.43) | GAAL3MBTL1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230144767-A1 | TARGETED NITROXIDE AGENTS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230144767-A1 | TARGETED NITROXIDE AGENTS | TXNRD2, TXN2, HSPE1 | GAA 2457/4885L3MBTL1 1197/4885CA1 3521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.