Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 11/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30620432 | 0.84 | OGA (0.73) | OGA | |
| SCHEMBL29057518 | 0.82 | OGA (0.77) | OGASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL29057475 | 0.82 | OGA (0.75) | OGASIGMAR1TSHRALDH1A1LMNA | |
| SCHEMBL30440214 | 0.81 | OGA (0.44) | OGASMN1; SMN2TSHRCYP2C19RECQL | |
| SCHEMBL29057446 | 0.81 | OGA (0.77) | OGASMN1; SMN2TSHRMAPTALDH1A1 | |
| SCHEMBL29057480 | 0.81 | OGA (0.77) | OGASMN1; SMN2TSHRMAPTALDH1A1 | |
| SCHEMBL29057450 | 0.81 | OGA (0.77) | OGASMN1; SMN2TSHRMAPTALDH1A1 | |
| SCHEMBL29057427 | 0.81 | OGA (0.77) | OGAALDH1A1KDM4E | |
| SCHEMBL29057492 | 0.78 | OGA (0.79) | OGALMNAMEN1KMT2A | |
| SCHEMBL10233603 | 0.76 | MAPT (0.41) | OGASMN1; SMN2TSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116438167-A | Compounds having O-GlcNAc enzyme inhibitory activity and uses thereof | 美迪福伦DBT有限公司 | 2023-07-14 | — | — | CN | disclosed |