Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.48 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ASPH | Q12797 | 1/20 | 0.44 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.44 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11410233 | 1.00 | LIPE (0.50) | LIPEKMT2AP4HTMTRPC6RAB9A | |
| SCHEMBL11412080 | 0.84 | CDK8 (0.55) | — | |
| SCHEMBL753336 | 0.82 | P4HTM (0.53) | P4HTMKDM4EP4HA1MIF | |
| SCHEMBL5755276 | 0.82 | P4HTM (0.63) | P4HTMKDM4ELMNAP4HA1MIF | |
| SCHEMBL211804 | 0.81 | KMT2A (0.70) | KMT2AP4HTMRAB9AKDM4EASPH | |
| SCHEMBL31532327 | 0.81 | KMT2A (0.70) | KMT2AP4HTMRAB9AKDM4EASPH | |
| SCHEMBL3992720 | 0.80 | SCN9A (0.47) | KDM4EASPHRIOX2KDM8 | |
| SCHEMBL17157312 | 0.80 | LIPE (0.45) | LIPEKMT2ATRPC6RAB9AMAPK14 | |
| Hydrochloric Acid SCHEMBL9779782 | 0.80 | KMT2A (0.68) | KMT2AP4HTMRAB9AKDM4EASPH | |
| SCHEMBL11411697 | 0.79 | P4HTM (0.58) | P4HTMKDM4EASPHRIOX2KDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111527078-B | Pyridinecarbonyl derivatives and their therapeutic use as TRPC6 inhibitors | 勃林格殷格翰国际公司 | 2023-06-02 | — | — | CN | disclosed |