Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 17/20 | 1.00 |
| ▸ | WNT3A | P56704 | 17/20 | 1.00 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15969389 | 1.00 | CTNNB1 (1.00) | CTNNB1WNT3AACHEHTR4SIGMAR1 | |
| SCHEMBL15969767 | 0.84 | CTNNB1 (1.00) | CTNNB1WNT3AACHEHTR4SIGMAR1 | |
| SCHEMBL30441374 | 0.84 | CTNNB1 (1.00) | CTNNB1WNT3AACHEHTR4SIGMAR1 | |
| SCHEMBL15969861 | 0.84 | CTNNB1 (1.00) | CTNNB1WNT3AACHEHTR4SIGMAR1 | |
| SCHEMBL15969364 | 0.83 | CTNNB1 (1.00) | CTNNB1WNT3AACHEHTR4SIGMAR1 | |
| SCHEMBL30441226 | 0.83 | CTNNB1 (1.00) | CTNNB1WNT3AACHEHTR4SIGMAR1 | |
| SCHEMBL15988721 | 0.83 | CTNNB1 (0.71) | CTNNB1WNT3AACHEHTR4SIGMAR1 | |
| SCHEMBL17929691 | 0.83 | CTNNB1 (0.75) | CTNNB1WNT3AACHEHTR4SIGMAR1 | |
| SCHEMBL15979946 | 0.82 | CTNNB1 (0.76) | CTNNB1WNT3AACHEHTR4SIGMAR1 | |
| SCHEMBL15979933 | 0.81 | CTNNB1 (0.74) | CTNNB1WNT3AACHEHTR4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11673885-B2 | γ-diketones as Wnt/β-catenin signaling pathway activators | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11673885-B2 | γ-diketones as Wnt/β-catenin signaling pathway activators | GSK3A, GSK3B, WNT1 | CTNNB1 5/4885WNT3A 4/4885ACHE 1330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.