Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 8/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10814246 | 0.83 | DRD1 (0.54) | CYP3A4CYP2D6DRD1MAPK1THPO | |
| SCHEMBL30446444 | 0.81 | KDM4E (0.50) | CYP3A4MAPK1THPOKDM4EMAPT | |
| SCHEMBL6558562 | 0.81 | DDB1 (0.47) | DDB1CRBNCYP3A4CYP2D6DRD1 | |
| SCHEMBL2045579 | 0.74 | PDE4A (0.51) | CYP3A4CYP2D6LMNA | |
| SCHEMBL6557753 | 0.73 | DDB1 (0.51) | DDB1CRBNCYP3A4CYP2D6CYP19A1 | |
| SCHEMBL27211314 | 0.72 | GRM1 (0.44) | DDB1CRBNMAPK1 | |
| SCHEMBL11616959 | 0.72 | DRD1 (0.43) | CYP2D6DRD1MAPK1THPOHIF1A | |
| SCHEMBL6558371 | 0.70 | HTT (0.47) | HSD17B10KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL6556640 | 0.69 | CYP3A4 (0.42) | CYP3A4CYP2D6DRD1MAPT | |
| SCHEMBL11616505 | 0.69 | DRD2 (0.46) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997311-B | Asymmetric 4-pyridine substituted 3, 5-diarylmethylene-4-piperidone and preparation method thereof | 滨州医学院 | 2023-06-23 | — | — | CN | disclosed |