Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.32 |
| ▸ | WNT3A | P56704 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1481530 | 0.87 | PTPN1 (0.41) | PTPN1GSK3BCTNNB1WNT3A | |
| SCHEMBL30440840 | 0.85 | ALDH1A1 (0.37) | GSK3BDRD2CTNNB1WNT3A | |
| SCHEMBL29973872 | 0.81 | CYP2C9 (0.40) | — | |
| SCHEMBL29974224 | 0.80 | PARP1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL31473113 | 0.78 | PARP1 (0.43) | — | |
| SCHEMBL636844 | 0.76 | CTNNB1 (0.46) | PTPN1GSK3BCTNNB1WNT3A | |
| SCHEMBL1067879 | 0.76 | KDM4E (0.43) | — | |
| SCHEMBL29974429 | 0.76 | KDM4E (0.43) | — | |
| SCHEMBL31405456 | 0.74 | ABCG2 (0.34) | — | |
| SCHEMBL25198601 | 0.74 | PDE4B (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850251-B | 3, 4-methylenedioxyacetophenone imidazole oxime ether derivative, preparation method and application thereof, and medicine for treating Alzheimer's disease | 西北农林科技大学 | 2024-04-12 | — | — | CN | disclosed |
| CN-115850251-A | 3,4-methylenedioxyacetophenone imidazole oxime ether derivative, preparation method and application thereof, and medicine for treating Alzheimer's disease | 西北农林科技大学 | 2023-03-28 | — | — | CN | disclosed |