Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | AGXT | P21549 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1262764 | 1.00 | DPP4 (0.33) | DPP4KDM1AKCNH2KDM1BIDO1 | |
| SCHEMBL377065 | 0.90 | KDM1A (0.41) | DPP4KDM1AKCNH2KDM1BIDO1 | |
| SCHEMBL29545980 | 0.90 | KDM1A (0.41) | DPP4KDM1AKCNH2KDM1BIDO1 | |
| SCHEMBL21521510 | 0.87 | KDM1A (0.38) | DPP4KDM1AKCNH2KDM1BPTPN1 | |
| SCHEMBL2528520 | 0.85 | KDM1A (0.36) | KDM1AKCNH2KDM1BPTPN1 | |
| SCHEMBL16860902 | 0.85 | DPP4 (0.33) | DPP4PTPN1 | |
| SCHEMBL344590 | 0.81 | DPP4 (0.46) | DPP4 | |
| SCHEMBL27893578 | 0.81 | KDM1A (0.31) | KDM1AKCNH2KDM1B | |
| SCHEMBL18226969 | 0.81 | DPP4 (0.39) | DPP4IDO1AGXT | |
| SCHEMBL28490129 | 0.79 | KDM1A (0.38) | KDM1AKDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496142-A | Aryl alkylamine compound and preparation method and application thereof | 仁合益康集团有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-110088089-B | Benzyl amino pyridyl cyclopropane carboxylic acid, pharmaceutical composition and application thereof | 勃林格殷格翰国际有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-110177773-B | Benzyl aminopyridine cyclopropanecarboxylic acid, pharmaceutical composition and application thereof | 勃林格殷格翰国际有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-110248929-B | Benzyl amino pyrazinyl cyclopropanecarboxylic acid, pharmaceutical composition and use thereof | 勃林格殷格翰国际有限公司 | 2023-05-12 | — | — | CN | disclosed |